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Editorial
Neurology
Recent studies are focus on the new treatments for hypoxicischemic encephalopathy (HIE) and long-term outcomes in later childhood and adolescence in children with a history on HIE
Eun Sook Suh
Clin Exp Pediatr. 2021;64(12):628-629.   Published online September 30, 2021
Neonatal encephalopathy is the most important reason for morbidity and mortality. The early detection of neonate with high risk for hypoxic ischemic encephalopathy (HIE) and treatment are important for prevent long term complication. Hypothermia is currently standard treatment option for HIE. Several clinical studies have been performed due to improve the long term outcome. New therapeutic options including xenon, allopurinol, erythropoietin, topiramate will help to reduce neuropsychiatric disability.
Case Report
New daily persistent headache with isolated sphenoiditis in children
Jeongho Lee, Minhee Rhee, Eun Sook Suh
Clin Exp Pediatr. 2015;58(2):73-76.   Published online February 28, 2015

Isolated sphenoid sinusitis is a rare disease in children, and its symptoms are often nonspecific and confusing. Rarely, severe headache can be the first or only symptom of isolated sphenoid sinusitis. New daily persistent headache (NDPH) is a form of chronic daily headache that may have features of both migraines and tension-type headaches. NDPH is difficult to diagnose and requires...

Toxic epidermal necrolysis induced by lamotrigine treatment in a child
Youngsuk Yi, Jeong Ho Lee, Eun Sook Suh
Clin Exp Pediatr. 2014;57(3):153-156.   Published online March 31, 2014

Toxic epidermal necrolysis is an unpredictable and severe adverse drug reaction. In toxic epidermal necrolysis, epidermal damage appears to result from keratinocyte apoptosis. This condition is triggered by many factors, principally drugs such as antiepileptic medications, antibiotics (particularly sulfonamide), nonsteroidal anti-inflammatory drugs, allopurinol, and nevirapine. Lamotrigine has been reported potentially cause serious cutaneous reactions, and concomitant use of valproic acid...

Review Article
Neonatal seizures in Korea, 1983-2009
Eun Sook Suh
Clin Exp Pediatr. 2009;52(9):957-963.   Published online September 15, 2009
Neonatal seizures are the most common and distinctive clinical sign of prenatal and/or neonatal brain disorders. Newborn infants with seizures are at risk of mortality and survivors at risk for neurologic impairment, developmental delay, and subsequent epilepsy. Fifteen reports on neonatal seizures in Korea from 1983 to 2009 were analyzed. A total of 731 neonatal seizure cases were reported. Day...
Case Report
A case of antiepileptic drug hypersensitivity syndrome by lamotrigine mimicking infectious mononucleosis and atypical Kawasaki disease
Su Jung Yoo, Ihl Sung Park, Eun Sook Suh
Clin Exp Pediatr. 2009;52(3):389-391.   Published online March 15, 2009
AHS는 항경련제에 의한 부작용으로 드물게 발생하지만 생명을 위협할 수 있는 지연형 면역반응이다. 보통 항경련제 복용 후 1-8주 사이에 고열, 피부발진, 림프절병증의 임상 증세를 나타내고, 혈액, 간, 신장, 또는 폐 등의 내부 장기를 침범한다. AHS는 항경련제에 의한 부작용으로 증상이 전신적으로 다양하게 나타날 수 있다. 그리고 전염성 단핵구증이나 가와사키병과 같은 전신적 질환들과도 유사한 임상증상들을 보이기 때문에 이런 질환들과 감별하는 것이 중요하고 사망률도...
A case of acute transverse myelitis following chickenpox
Min Young Kim, Eun Sook Suh
Clin Exp Pediatr. 2009;52(3):380-384.   Published online March 15, 2009
Acute transverse myelitis (ATM) in most patients is characterized by an abrupt onset of progressive weakness and sensory disturbance in the lower extremities with a preceding viral infection such as Epstein-Barr, herpes simplex, influenza, mumps and Varicella-zoster viruses (VZV). Although less frequent, some residual deficits including bladder dysfunction or weakness in the lower extremities may follow ATM, from which recovery...
Review Article
Nonepileptic paroxysmal disorders in childhood
Eun Sook Suh
Clin Exp Pediatr. 2006;49(4):364-367.   Published online April 15, 2006
Epilepsy is the most common paroxysmal disorders seen in the childhood. But other nonepileptic paroxysmal events are confused with epileptic seizures or have unusual clinical features. Nonepileptic paroxysmal disorders tend to recur episodically. So differential diagnosis between epileptic and nonepileptic disorders in fundamental not only to allow correct management of patients and but also avoid of unnecessary antiepileptic medications. To...
Clinical Lecture
Cognitive Dysfunction in Children
Eun Sook Suh
Clin Exp Pediatr. 2004;47(4):351-354.   Published online April 15, 2004
Cognition is a broad term that include a range of abilities such as memory, perception, attention, organization, planning, problem solving abilities and the perception of another person's unconscious motivation. Cognitive dysfunction is an abnormality of the central nervous system, manifest during the developmental period, which result significant life long impairment. The neurologic assessment of the delayed or retarded child emphasizes...
Case Report
A Case of Ileocolic Type Intussusception Associated with Hematemesis
Young Hee Kim, Seung Soo Kim, Eun Sook Suh
Clin Exp Pediatr. 2003;46(7):722-725.   Published online July 15, 2003
Intussusception is a common cause of lower intestinal bleeding from five to 11 months of age. Typical symptoms are paroxysmal colicky pain, irritability, vomiting, abdominal mass and currant jelly stool, but hematemesis is rare. Though the most common type of intussusception is ileocecal type, it is rarely accompanied with hematemesis. Up until the present, hematemesis has been observed rarely but...
Original Article
Electroencephalogram in Phenylketonuria
Sang Hyun Kim, Eun Sook Suh, Dong Hwan Lee
Clin Exp Pediatr. 1997;40(1):13-20.   Published online January 15, 1997
Therapeutic effects of plasmapheresis in Guillian-Barre syndrome.
Sung Jin Chang, Sun Hee Jung, Eun Sook Suh, Chin Moo Kang
Clin Exp Pediatr. 1991;34(1):66-73.   Published online January 31, 1991
Although the exact mechanism of the immunologic injury is unknown, the pathogenesis of the Guillain-Barr受 syndrome is explained as an autoimmune attack directed against to peripheral nervous myelin. So plasmapheresis is tried for treatment of Guillain-Barr즌 syndrome. Authors analysed 12 cases af Guillain-Barr受 syndrome who were treated with plasmapheresis and compared the results with that of the 13 cases, treated with conventional therapy. Duration between...
A Case of Dermatomyositis.
Pal Dong Kim, Chi Han Kwon, Eun Sook Suh, Chin Moo Kang
Clin Exp Pediatr. 1990;33(6):870-878.   Published online June 30, 1990
Dermatomyositis is a rarely recognized disorder with poor prognosis. The mortality has been decreased after the initiation of steroid for ifs treatment. Authors experienced a case of der- matomyositis responded well to prednisone therapy and developed hyperglycemia laterly. A 14 year old boy was admitted to pediatric ward with the chief complaints of progressive muscular weakness and facial rash and diagnosed as having dermatomyositis...
Four Cases of Childhood Systemic Lupus Erythematosus.
Jun Ah Jeong, Young Mi Kim, Eun Sook Suh, Sung Ho Kim, Chin Moo Kang, Sang Sook Lee, Chai Hong Chung
Clin Exp Pediatr. 1990;33(2):264-273.   Published online February 28, 1990
Systemic Lupus Erythematosus (SLE) is a rare entity in pediatric age and prognosis is poor due to higher incidence of renal involvement in children. Authors experienced four cases of SLE, aged between 9-13 years. All cases were female. The diagnosis was based on “The 1982 revised criteria for SLE (by American Rheumatism Association). All cases had fever on admission and the butterfly facial rash was...
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